F. Lamarche, M. Agharazii, A. C. Nadeau-Fredette, F. Madore, R. Goupil, Central and Brachial Blood Pressures, Statins, and Low-Density Lipoprotein Cholesterol: A Mediation Analysis, Hypertension 71(3):415-421

M. J. Favé, F. C. Lamaze, D. Soave, A. Hodgkinson, H. Gauvin, V. Bruat, J.C. Grenier, E. Gbeha, K. Skead, A. Smargiassi, M. Johnson, Y. Idaghdour, P. Awadalla, Gene-by-environment interactions in urban populations modulate risk phenotypes, Nat Commun. 9(1):827

D. Nada, C. Julien, M. E. Samuels, A. Moreau, A Replication Study for Association of LBX1 Locus With Adolescent Idiopathic Scoliosis in French-Canadian Population, Spine (Phila Pa 1976) 43(3):172-178

S. Peischl, I. Dupanloup, A. Foucal, M. Jomphe, V. Bruat, J.-C. Grenier, A. Gouy, K. J. Gilbert, E. Gbeha, L. Bosshard, E. Hip-Ki, M. Agbessi, A. Hodgkinson, H. Vézina, P. Awadalla, L. Excoffier, Relaxed Selection During a Recent Human Expansion, Genetics 208(2):763-777


F. Lepeytre, P. L. Lavoie, S. Troyanov, F. Madore, M. Agharazii, R. Goupil, Uric acid association with pulsatile and steady components of central and peripheral blood pressures, Journal of Hypertension 0263-6352

D. A. Knowles, J. R. Davis, H. Edgington, A. Raj, M. J. Favé, X. Zhu, J. B. Potash, M. M. Weissman, J. Shi, D. Levinson, P. Awadalla, S. Mostafavi, S. B. Montgomery, A. Battle, Allele-specific expression reveals interactions between genetic variation and environment, Nature Methods 14(7):699-702

A. Gravel, I. Dubuc, A. Brooks-Wilson, K. J. Aronson, J. Simard, H. A. Velásquez-García, J. J. Spinelli, L. Flamand, Inherited Chromosomally Integrated Human Herpesvirus 6 and Breast Cancer, Cancer Epidemiol Biomarkers Prev 26(3):425-427

C. Dias, M. Giordano, R. Frechette, S. Bellone, C. Polychronakos, L. Legault, C. L. Deal, C. G. Goodyer, Genetic variations at the human growth hormone receptor (GHR) gene locus are associated with idiopathic short stature, J Cell Mol Med 21(11):2985-2999

S. Bernatsky, A. Smargiassi, L. Joseph, P. Awadalla, I. Colmegna, M. Hudson, M.J. Fritzler, Industrial air emissions, and proximity to major industrial emitters, are associated with anti-citrullinated protein antibodies, Environ Res 157:60-63


K. R. Kukurba, P. Parsana, B. Balliu, K. S. Smith, Z. Zappala, D. A. Knowles, M. J. Favé, J. R. Davis, X. Li, X. Zhu, J. B. Potash, M. M. Weissman, J. Shi, A. Kundaje, D. F. Levinson, P. Awadalla, S. Mostafavi, A. Battle, S. B. Montgomery, Impact of the X Chromosome and sex on regulatory variation, Genome Res. 26(6):768-77

S. Troyanov, C. Delmas-Frenette, G. Bollee, S. Youhanna, V. Bruat, P. Awadalla, O. Devuyst and F. Madore, Clinical, Genetic, and Urinary Factors Associated with Uromodulin Excretion, Clin J Am Soc Nephrol 11(1): 62-69

A. Hodgkinson, J.-C. Grenier, E. Gbeha, P. Awadalla, Haplotype-based normalization technique for the analysis and detection of allele specific expression, BMC Bioinformatics 17(1): 364

N. D. Merner, A. Mercado, A. R. Khanna, A. Hodgkinson, V. Bruat, P. Awadalla, G. Gamba, G. A. Rouleau and K. T. Kahle, Gain-of-function missense variant in SLC12A2, encoding the bumetanide-sensitive NKCC1 cotransporter, identified in human schizophrenia, J Psychiatr Res 77: 22-26

R. Goupil, D. Dupuis, S. Troyanov, F. Madore and M. Agharazii, Heart rate dependent and independent effects of beta-blockers on central hemodynamic parameters: a propensity score analysis, J Hypertens 34(8): 1535-1543

R. Goupil, D. Dupuis, M. Agharazii, P. Hamet, S. Troyanov and F. Madore, Central blood pressures in early chronic kidney disease: an analysis of CARTaGENE, Nephrol Dial Transplant 32(6):976-983

S. S. Anand, J. V. Tu, P. Awadalla, S. Black, C. Boileau, D. Busseuil, D. Desai, J. P. Despres, R. J. de Souza, T. Dummer, S. Jacquemont, B. Knoppers, E. Larose, S. A. Lear, F. Marcotte, A. R. Moody, L. Parker, P. Poirier, et al., Rationale, design, and methods for Canadian alliance for healthy hearts and minds cohort study (CAHHM) - a Pan Canadian cohort study, BMC Public Health 32(6):976-983


J. G. Hussin, A. Hodgkinson, Y. Idaghdour, J. C. Grenier, J. P. Goulet, E. Gbeha, E. Hip-Ki and P. Awadalla, Recombination affects accumulation of damaging and disease-associated mutations in human populations, Nat Genet 47(4): 400-404

R. El-Bikai, M. R. Tahir, J. Tremblay, M. Joffres, O. Seda, L. Sedova, P. Awadalla, C. Laberge, B. M. Knoppers, P. Dumas, D. Gaudet, L. G. Ste-Marie and P. Hamet, Association of age-dependent height and bone mineral density decline with increased arterial stiffness and rate of fractures in hypertensive individuals, J Hypertens 33(4): 727-735

A. Gravel, I. Dubuc, G. Morissette, R.H. Sedlak, K. R. Jerome, L. Flamand, Inherited chromosomally integrated human herpesvirus 6 as a predisposing risk factor for the development of angina pectoris, Proc Natl Acad Sci U S A 112(26):8058-63

C. S. Moura, S. S. Daskalopoulou, L. E. Levesque, S. Bernatsky, M. Abrahamowicz, M. A. Tsadok, S. Rajabi and L. Pilote, Comparison of the Effect of Thiazide Diuretics and Other Antihypertensive Drugs on Central Blood Pressure: Cross-Sectional Analysis Among Nondiabetic Patients, J Clin Hypertens (Greenwich) 17(11): 848-854


J. C. Verhave, S. Troyanov, F. Mongeau, L. Fradette, J. Bouchard, P. Awadalla and F. Madore, Prevalence, awareness, and management of CKD and cardiovascular risk factors in publicly funded health care, Clin J Am Soc Nephrol 9(4): 713-719

A. Hodgkinson, Y. Idaghdour, E. Gbeha, J. C. Grenier, E. Hip-Ki, V. Bruat, J. P. Goulet, T. de Malliard and P. Awadalla, High-resolution genomic analysis of human mitochondrial RNA sequence variation, Science 344(6182): 413-415

K. T. Kahle, N. D. Merner, P. Friedel, L. Silayeva, B. Liang, A. Khanna, Y. Shang, P. Lachance-Touchette, C. Bourassa, A. Levert, P. A. Dion, B. Walcott, D. Spiegelman, A. Dionne-Laporte, A. Hodgkinson, P. Awadalla, H. Nikbakht, J. Majewski, P. Cossette, Genetically encoded impairment of neuronal KCC2 cotransporter function in human idiopathic generalized epilepsy, EMBO Rep 15(7): 766-774


D. Doiron, P. Raina, I. Fortier; Linkage Between Cohorts and Health Care Utilization Data: Meeting of Canadian Stakeholders workshop participants, Linking Canadian population health data: maximizing the potential of cohort and administrative data, Canadian Journal of Public Health 104(3): e258–e261

P. Awadalla, C. Boileau, Y. Payette, Y. Idaghdour, J. P. Goulet, B. Knoppers, P. Hamet, C. Laberge and C. A. Project, Cohort profile of the CARTaGENE study: Quebec's population-based biobank for public health and personalized genomics, Int J Epidemiol 42(5): 1285-1299


S. Fortin, S. Pathmasiri, R. Grintuch and M. Deschenes, Access arrangements' for biobanks: a fine line between facilitating and hindering collaboration, Public Health Genomics 14(2): 104-114



Y. Joly and B. M. Knoppers, Pharmacogenomic data sample collection and storage: ethical issues and policy approaches, Pharmacogenomics 7(2): 219-226


B. Godard, J. Marshall, C. Laberge and B. M. Knoppers, Strategies for consulting with the community: the cases of four large-scale genetic databases, Sci Eng Ethics 10(3): 457-477



Role of Prohibitins and SUMOylation in Osteoarthritis Pathogenesis Chercheur principal: Alain Moreau

Affiliation: Centre Hospitalier Universitaire Sainte-Justine


Genetics of REM sleep behavior disorder and conversion to Parkinson's disease Chercheur principal: Ziv Gan Or

Affiliation: McGill University

Marqueurs Ostéocytaires, Fractures et Évènements Cardiovasculaires en Insuffisance Rénale Chronique (MOFECIRC) Chercheur principal: Fabrice Mac-Way

Affiliation: Université Laval

Comparative Genomewide Association of Aortic Stenosis With and Without Coronary Artery Disease Chercheur principal: George Thanassoulis

Affiliation: McGill University Health Centre

Occupational Physical Activity and Lung Cancer Chercheur principal: Vikki Ho

Affiliation: CRCHUM

Genetic analyses of cardiometabolic diseases and traits in CARTaGENE Chercheur principal: Guillaume Lettre

Affiliation: Institut de Cardiologie de Montréal Centre de Recherche

The impact of structural genomic variants on cognition in the general population Chercheur principal: Sébastien Jacquemont

Affiliation: CHU Sainte-Justine

Systemic inflammation and the risk of depression in people with type 2 diabetes: a prospective community study Chercheur principal: Norbert Schmitz

Affiliation: Douglas Mental Health University Institute

Pharmacogenetic study exploring the impact of a genetic variant in the CYP2R1 gene on the response to vitamin D replacement therapy Chercheur principal: Brent Richards

Affiliation: Lady Davis Institute - Jewish General Hospital

Evaluation of genetic variants identified through hereditary cancer gene discovery projects in a French Canadian control cohort Chercheur principal: William Foulkes

Affiliation: McGill University Health Centre

Genetic basis and modifiers of sleep disorders Chercheur principal: Simon Warby

Affiliation: Hôpital Sacré-Coeur de Montréal

Estimation de la prévalence de certaines mutations associées à un risque accru de cancer du sein, ainsi que du risque qui leur sont associées Chercheur principal: Jacques Simard

Affiliation: CHU de Québec

SNP discovery in myalgic encephalomyelitis (ME) Chercheur principal: Alain Moreau

Affiliation: CHU Ste-Justine


Genomic follow-up of the susceptibility loci for schizophrenia and bipolar disorder in multi-affected families of Eastern Quebec Chercheur principal: Michel Maziade

Affiliation: Université Laval

Poor sleep and mental health: independent or overlapping risk factors for heart diseases? Chercheur principal: Norbert Schmitz

Affiliation: Institut de santé mentale Douglas, Université McGill

Genomic Analysis of the Mitochondrial Transcriptome Chercheur principal: Alan Hogkinson

Affiliation: King's College London

L'étude du rôle prédicteur de la pression aortique centrale dans la survenue d'événements cardiovasculaires Chercheur principal: Rémi Goupil

Affiliation: Hôpital Sacré-Coeur de Montréal

Deciphering the Genetic background of Restless Legs Syndrome Chercheur principal: Guy Rouleau

Affiliation: Institut neurologique de Montréal, Université McGill


Vegetarian diet, the metabolic syndrome, obesity and inflammatory status Chercheur principal: Isabel Fortier

Affiliation: Maelstrom, Université McGill

Comparative Effectiveness Research in the Canadian Partnership for Tomorrow Cohort Chercheur principal: Sasha Bernatsky

Affiliation: Centre de santé de l’Université McGill

Identification of genes involved in adolescent idiopathic Scoliosis Chercheur principal: Alain Moreau

Affiliation: CHU Sainte-Justine

Evaluation of coronary vascular disease among high cardiovascular risk patients in CARTaGENE Chercheur principal: Thao Huynh

Affiliation: Sanofi

Canadian Alliance for Healthy Hearts and Minds – Development of community health and health services profiles Chercheur principal: Jack Tu

Affiliation: Sunnybrook Health Sciences Centre

Simultaneous systematic monitoring of hormonal pathways in bipolar disorder using LC-based targeted and untargeted metabolomics Chercheur principal: Dajana Vuckovic

Affiliation: Université Concordia

Clinical implementation and Outcomes Evaluation of Blood-Based biomarkers for COPD management Chercheur principal: Elizabeth MacNamara

Affiliation: Hôpital général juif


The genome-wide association study of the principal components of the metabolic syndrome enriched with albumin/creatinine ratio regarding the OPTI-THERA research project Chercheur principal: Pavel Hamet

Affiliation: CHUM

Exploring the Potential of CARTaGENE for GIS-Based Epidemiology: A Pilot Study of Green Space and Mental Health Chercheur principal: Nolwenn Noisel

Affiliation: CHU Sainte-Justine, Université de Montréal

Human Growth Hormone Receptor: regulation of expression during development Chercheur principal: Cynthia Goodyer

Affiliation: Université McGill

Génétique de la Rhinosinusite chronique avec polypose nasale Chercheur principal: Martin Desrosiers

Affiliation: CHUM

The association between type II diabetes and physical activity in the Canadian Partnership for Tomorrow Project Chercheur principal: Zhijie (Michael) Yu

Affiliation: Dalhousie University

Étude bien-être émotionnel, facteurs métaboliques et l’état de santé Chercheur principal: Norbert Schmitz

Affiliation: Institut de santé mentale Douglas, Université McGill


Prévalence de l’insuffisance rénale chronique dans la cohorte CARTaGENE (2) Chercheur principal: François Madore

Affiliation: Hôpital Sacré-Coeur

Caractérisation des contributions génomiques et environnementales à la variation des phénotypes cardiovasculaires et métaboliques dans la population du Québec Chercheur principal: Philip Awadalla

Affiliation: CHU Sainte-Justine, Université de Montréal

Plateforme d’Innovation en Génomique des Scolioses Pédiatriques (GSP) : Des Gènes aux Tests - Diagnostiques Complets Chercheur principal: Alain Moreau

Affiliation: CHU Ste-Justine

Molecular dissection of congenital heart disease in the French Canadian population Chercheur principal: Gregor Andelfinger

Affiliation: CHU Ste-Justine


Analyse des caractéristiques généalogiques des participants au projet CARTaGENE Chercheur principal: Marc Tremblay

Affiliation: Université du Québec à Chicoutimi

Environment, Epigenetics, and Rheumatic Disease Chercheur principal: Sasha Bernatsky

Affiliation: Centre de santé de l’Université McGill

Conséquences médicales de l’intégration chromosomique de l’herpès virus humain 6 Chercheur principal: Louis Flamand

Affiliation: Université Laval

Test de l’accumulation de mutations délétères lors d’expansions spatiales par séquençage d’exomes Chercheur principal: Laurent Excoffier

Affiliation: Université de Berne, Suisse

Comparative Effectiveness Research in the Canadian Partnership for Tomorrow Cohort Chercheur principal: Sasha Bernatsky

Affiliation: Centre de santé de l’Université McGill

Développement d’une plateforme pour le diagnostic moléculaire du syndrome de Zellweger au Québec Chercheur principal: Luigi Bouchard

Affiliation: Université de Sherbrooke


Prévalence de l’insuffisance rénale chronique dans la cohorte CARTaGENE (1) Chercheur principal: François Madore

Affiliation: Hôpital Sacré-Coeur


Methylmercury exposure and urinary metabolic profile in Cree people from Northern Quebec Chercheur principal: Pierre Ayotte

Affiliation: Centre de recherche du CHUQ, Université Laval